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      <image:title>Our Mission</image:title>
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      <image:title>Our Mission - OUR MISSION</image:title>
      <image:caption>Our mission is to develop a pipeline of best-in-class oncolytic immunotherapeutics that are highly effective in treating patients with solid cancers. At Seneca Therapeutics, we believe a cure for cancer is within our lifetime and we are working with urgency to see this promising possibility become a reality.</image:caption>
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      <image:title>Our Mission - OUR VISION</image:title>
      <image:caption>Seneca Therapeutics, Inc. (Seneca) is developing a pipeline of novel cancer agents using the nonpathogenic Seneca Valley Virus isolate 001 (SVV-001). Our first product, SVV-001 is being administered intratumorally in an Investigator Initiated Trial titled, “A Phase 1 Trial of the Oncolytic Virus SVV-001 in Combination with Nivolumab and Ipilimumab in Patients with Poorly Differentiated Neuroendocrine Carcinomas or Well-Differentiated High-Grade (Grade 3) Neuroendocrine Tumors”. SVV-001 is a targeted immunotherapy that selectively kills cancer cells expressing the SVV-001 receptor, TEM8.  SVV-001 converts the tumor microenvironment from T-Cell resistant (“cold”) to T-Cell permissive (“Hot”). SVV-001 synergizes with immune checkpoint inhibitors and other cancer agents to significantly benefit cancer patients .</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Our Team (Copy)</image:title>
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      <image:title>Home  (Copy) - Transient (Copy) (Copy)</image:title>
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    <lastmod>2023-09-13</lastmod>
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      <image:title>KOL WEBINAR ON SENECA VALLEY VIRUS &amp; TEM 8</image:title>
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      <image:title>Patient Screening Test For Patient Selection - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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    <image:image>
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      <image:title>Patient Screening Test For Patient Selection - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Seneca's primary asset, SVV-001, is an oncolytic virus that selectively replicates in tumor cells expressing the TEM8 receptor, while being non-pathogenic in both humans and animals. Extensively evaluated in over 30 preclinical cancer models and three clinical trials for solid cancers including neuroendocrine and pediatric tumors. Combining SVV-001 with immune modulators, cytokines, and checkpoint inhibitors has shown synergistic anti-tumor effects in various animal studies.</image:caption>
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      <image:title>Home - KOL WEBINAR ON SENECA VALLEY VIRUS &amp; TEM 8</image:title>
      <image:caption>In this KOL Webinar, SVV is being analyzed as an ideal cancer therapeutic by explaining advances from an structural biology perspective (Mihnea Bostina), clinical perspective (Aman Chauhan) and industry perspective (Paul Hallenbeck).</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Jayawardena et al. 2018. Proc Natl Acad Sci U S A. 2018 Nov 13; 115(46): E10934–E10940.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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